Lecture 11 – Bone Cells

There are five main types of bone cells in bone tissue.

Osteogenic Cells– respond to traumas such as fractures, by giving rise to bone-forming cells (osteoblasts) and bone destroying cells (osteoclasts).

Osteoblasts – (Bone forming cells)

-synthesize and secrete un-mineralized ground substance

-found in areas of high metabolism within the bone

Osteocytes – Control Ca++ release from bone tissue to blood

Ostecytes are mature bone cells that are made from osteoblasts that have connective tissue around themselves.  These cells maintain healthy bone tissue by secreting enzymes and controlling bone mineral content.

Osteoclasts – Large cells that break down bone tissue.  Important: Bone growth, healing, and remodeling.

Bone lining cells – Made from osteoclasts along surface of most bones in an adult.  It is believed that these cells regulate movement of Ca++  and PO4 into and out of bone.



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